Generic Zofran is used to prevent nausea and vomiting that may be caused by surgery or by medicine to treat cancer (chemotherapy or radiation). Ondansetron blocks the actions of chemicals in the body that can trigger nausea and vomiting.

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Ondansetron Hydrochloride tablet

What is this medicine?

ONDANSETRON is used to treat nausea and vomiting caused by chemotherapy. It is also used to prevent or treat nausea and vomiting after surgery.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • liver disease
  • an unusual or allergic reaction to ondansetron, granisetron, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • carbamazepine
  • rifabutin
  • rifampin
  • rifapentine
  • St. John's wort
  • tramadol

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • difficulty breathing, wheezing, shortness of breath
  • fast or irregular heartbeat
  • fever and chills
  • tightness in the chest
  • skin rash, itching
  • swelling of the face, tongue, throat, hands and feet

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation or diarrhea
  • dizziness
  • headache

This list may not describe all possible side effects.

What should I watch for while taking this medicine?

Check with your doctor or health care professional right away if you have any sign of an allergic reaction.

Do not drink alcohol while taking this medicine.

Where can I keep my medicine?

Keep out of the reach of children.

Store between 2 and 30 degrees C (36 and 86 degrees F). Throw away any unused medicine after the expiration date.

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